Wile E. Coyote (Caninus Nervous Rex) pursues Road Runner (Burn-Em Uppus Asphaltus) and hurls a hand grenade which rebounds off a saguaro cactus.
Later attempts by the coyote include a bow, a hydraulic press activated by an electric eye, invisible paint, and a disguised shotgun. Finally, he rides a rocket, which goes the wrong way and sends him to the home of the Chinese Road Runner.
The title is a pun on the Leo Tolstoy novel War and Peace.
This was Chuck Jones' last Road Runner cartoon, and the last Chuck Jones-directed Warner Bros. cartoon to be released in the classic era.
The ABC version of this cartoon cuts the sequence where Wile E. Coyote disguises a double-barrel shotgun as a peep show (called "Secrets of a Harem") and ends up getting shot. Also cut was an early scene where a hand grenade ricochets back to Wile and blows him up (surprisingly, the end in which Wile E. Coyote ends up in China with a Chinese Road Runner was not cut, despite a similar scene being edited when ABC showed the Sylvester and Tweety cartoon "Tweety and the Beanstalk")
The Merrie Melodies Show on FOX shows the "Secrets of a Harem" sequence, but replaces the part where Wile gets shot with a frozen scene of the Road Runner looking down from a cliff.